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Antibody drug conjugates targeting HER2: Clinical development in metastatic breast cancer
The identification of the HER2 alteration as an actionable oncogenic driver in breast cancer has propelled the development of HER-targeting monoclonal antibodies (mAb) such as trastuzumab and pertuzumab, which led to dramatic improvements in survival outcomes. Lately, the great strides made toward d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636477/ https://www.ncbi.nlm.nih.gov/pubmed/36334569 http://dx.doi.org/10.1016/j.breast.2022.10.016 |