Reprogramming landscape highlighted by dynamic transcriptomes in therapy-induced neuroendocrine differentiation

Metastatic and locally advanced prostate cancer is treated by pharmacological targeting of androgen synthesis and androgen response via androgen signaling inhibitors (ASI), most of which target the androgen receptor (AR). However, ASI therapy invariably fails after 1–2 years. Emerging clinical evide...

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Detalles Bibliográficos
Autores principales: Asberry, Andrew Michael, Liu, Sheng, Nam, Hye Seung, Deng, Xuehong, Wan, Jun, Hu, Chang-Deng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Special Issue articles from "Computational single cell omics and drug discovery" edited by Pingzhao Hu
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636493/
https://www.ncbi.nlm.nih.gov/pubmed/36382181
http://dx.doi.org/10.1016/j.csbj.2022.10.031

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