The role of iron metabolism in chronic diseases related to obesity

Obesity is one of the major public health problems threatening the world, as well as a potential risk factor for chronic metabolic diseases. There is growing evidence that iron metabolism is altered in obese people, however, the highly refined regulation of iron metabolism in obesity and obesity-rel...

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Autores principales: Qiu, Fangyi, Wu, Lei, Yang, Guang, Zhang, Cong, Liu, Xiaofang, Sun, Xiance, Chen, Xin, Wang, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636637/
https://www.ncbi.nlm.nih.gov/pubmed/36335331
http://dx.doi.org/10.1186/s10020-022-00558-6
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author Qiu, Fangyi
Wu, Lei
Yang, Guang
Zhang, Cong
Liu, Xiaofang
Sun, Xiance
Chen, Xin
Wang, Ningning
author_facet Qiu, Fangyi
Wu, Lei
Yang, Guang
Zhang, Cong
Liu, Xiaofang
Sun, Xiance
Chen, Xin
Wang, Ningning
author_sort Qiu, Fangyi
collection PubMed
description Obesity is one of the major public health problems threatening the world, as well as a potential risk factor for chronic metabolic diseases. There is growing evidence that iron metabolism is altered in obese people, however, the highly refined regulation of iron metabolism in obesity and obesity-related complications is still being investigated. Iron accumulation can affect the body’s sensitivity to insulin, Type 2 diabetes, liver disease and cardiovascular disease. This review summarized the changes and potential mechanisms of iron metabolism in several chronic diseases related to obesity, providing new clues for future research.
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spelling pubmed-96366372022-11-06 The role of iron metabolism in chronic diseases related to obesity Qiu, Fangyi Wu, Lei Yang, Guang Zhang, Cong Liu, Xiaofang Sun, Xiance Chen, Xin Wang, Ningning Mol Med Review Obesity is one of the major public health problems threatening the world, as well as a potential risk factor for chronic metabolic diseases. There is growing evidence that iron metabolism is altered in obese people, however, the highly refined regulation of iron metabolism in obesity and obesity-related complications is still being investigated. Iron accumulation can affect the body’s sensitivity to insulin, Type 2 diabetes, liver disease and cardiovascular disease. This review summarized the changes and potential mechanisms of iron metabolism in several chronic diseases related to obesity, providing new clues for future research. BioMed Central 2022-11-05 /pmc/articles/PMC9636637/ /pubmed/36335331 http://dx.doi.org/10.1186/s10020-022-00558-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Qiu, Fangyi
Wu, Lei
Yang, Guang
Zhang, Cong
Liu, Xiaofang
Sun, Xiance
Chen, Xin
Wang, Ningning
The role of iron metabolism in chronic diseases related to obesity
title The role of iron metabolism in chronic diseases related to obesity
title_full The role of iron metabolism in chronic diseases related to obesity
title_fullStr The role of iron metabolism in chronic diseases related to obesity
title_full_unstemmed The role of iron metabolism in chronic diseases related to obesity
title_short The role of iron metabolism in chronic diseases related to obesity
title_sort role of iron metabolism in chronic diseases related to obesity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636637/
https://www.ncbi.nlm.nih.gov/pubmed/36335331
http://dx.doi.org/10.1186/s10020-022-00558-6
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