Chinese patients’ response to doctor–patient relationship stimuli: evidence from an event-related potential study

BACKGROUND: With improvements in medical technology, the doctor–patient relationship should be further improved. However, disputes between doctors and patients have increased, with the two groups frequently hurting each other. Therefore, we sought to explore the perception of Chinese patients regarding the stimuli of doctor–patient relationships with different valence. METHODS: We used event-related potential (ERP) to explore the brain electrical activity of 19 undergraduate participants who had a clinical experience in the previous 6 months where they perceived negative, neutral, and positive doctor–patient relationships. The ERPs were recorded, and the early ERP components (P2) and late positive potential (LPP) were measured. RESULTS: Compared with the stimuli of negative doctor–patient relationships, those of positive doctor–patient relationships would attract more attention and have larger P2 amplitude; LPP was larger for the stimuli of negative doctor–patient relationships than neutral ones in the 500–800 ms, while in the 1100–1500 ms, the stimuli of neutral doctor–patient relationships elicited larger LPP amplitude than positive ones. CONCLUSION: Patients paid more attention to the stimuli of positive doctor–patient relationships because they expected to have the same positive relationship. Although threatening elements in negative doctor–patient relationships would catch patients’ attention and make them have implicit emotional regulation, neutral stimuli with poker-faced doctors would cause lasting attention. These results illustrate the patients’ real perception of the different valence of doctor–patient relationship stimuli. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40359-022-00961-y.