The balance between NANOG and SOX17 mediated by TET proteins regulates specification of human primordial germ cell fate

BACKGROUND: Human primordial germ cells (hPGCs) initiate from the early post-implantation embryo at week 2–3 and undergo epigenetic reprogramming during development. However, the regulatory mechanism of DNA methylation during hPGC specification is still largely unknown due to the difficulties in ana...

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Detalles Bibliográficos
Autores principales: Li, Zili, Fang, Fang, Long, Yuting, Zhao, Qian, Wang, Xiaotong, Ye, Zhen, Meng, Tianqing, Gu, Xiuli, Xiang, Wenpei, Xiong, Chengliang, Li, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636699/
https://www.ncbi.nlm.nih.gov/pubmed/36333732
http://dx.doi.org/10.1186/s13578-022-00917-0

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