Cargando…

Irisin protects against obesity-related chronic kidney disease by regulating perirenal adipose tissue function in obese mice

BACKGROUND: Compared with typical visceral fat deposits in obesity and metabolic syndrome, perirenal adipose tissue (PRAT) dysfunction is more closely linked to obesity-related chronic kidney disease (OB-CKD). The myokine irisin reportedly promotes positive outcomes in metabolic disease. This study...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Fang, Kan, Chengxia, Wu, Di, Kuang, Zengguang, Song, Hongwei, Luo, Youhong, Zhang, Le, Hou, Ningning, Sun, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636726/ https://www.ncbi.nlm.nih.gov/pubmed/36335399 http://dx.doi.org/10.1186/s12944-022-01727-6

Ejemplares similares

Irisin: A Possible Marker of Adipose Tissue Dysfunction in Obesity
por: Tomasello, Laura, et al.
Publicado: (2023)

A hint for the obesity paradox and the link between obesity, perirenal adipose tissue and Renal Cell Carcinoma progression
por: Preza-Fernandes, José, et al.
Publicado: (2022)

Empagliflozin Attenuates Obesity-Related Kidney Dysfunction and NLRP3 Inflammasome Activity Through the HO-1–Adiponectin Axis
por: Ye, Tongtong, et al.
Publicado: (2022)

Integrated Proteomics and Metabolomics Analysis of Perirenal Adipose Tissue in Obese Rabbits Treated with a Restricted Diet
por: Shao, Jiahao, et al.
Publicado: (2021)

Novel insight into perirenal adipose tissue: A neglected adipose depot linking cardiovascular and chronic kidney disease
por: Huang, Na, et al.
Publicado: (2020)

Perirenal Adipose Tissue—Current Knowledge and Future Opportunities
por: Grigoraș, Adriana, et al.
Publicado: (2021)

Effect of Melatonin on Redox Enzymes Daily Gene Expression in Perirenal and Subcutaneous Adipose Tissue of a Diet Induced Obesity Model
por: Fernández-Mateos, Pilar, et al.
Publicado: (2023)

CB(1) Blockade Potentiates Down-Regulation of Lipogenic Gene Expression in Perirenal Adipose Tissue in High Carbohydrate Diet-Induced Obesity
por: Vida, Margarita, et al.
Publicado: (2014)

Effects of exercise and dietary intervention on muscle, adipose tissue, and blood IRISIN levels in obese male mice and their relationship with the beigeization of white adipose tissue
por: Li, Jing, et al.
Publicado: (2022)

The promotion of active aging through older adult education in the context of population aging
por: Zhang, Kexin, et al.
Publicado: (2022)

Integrated multi-omics analyses reveal effects of empagliflozin on intestinal homeostasis in high-fat-diet mice
por: Shi, Junfeng, et al.
Publicado: (2022)

Rapid Alterations in Perirenal Adipose Tissue Transcriptomic Networks with Cessation of Voluntary Running
por: Ruegsegger, Gregory N., et al.
Publicado: (2015)

Global Burden of cardiomyopathy and myocarditis in the older adults from 1990 to 2019
por: Zhang, Kexin, et al.
Publicado: (2022)

Perirenal Adipose Tissue Displays an Age-Dependent Inflammatory Signature Associated With Early Graft Dysfunction of Marginal Kidney Transplants
por: Boissier, Romain, et al.
Publicado: (2020)

Serum and Adipose Tissue mRNA Levels of ATF3 and FNDC5/Irisin in Colorectal Cancer Patients With or Without Obesity
por: Zhu, Huijuan, et al.
Publicado: (2018)

Modulation of Irisin and Physical Activity on Executive Functions in Obesity and Morbid obesity
por: Fagundo, A. B., et al.
Publicado: (2016)

Increased UCP1 expression in the perirenal adipose tissue of patients with renal cell carcinoma
por: Li, Xueqin, et al.
Publicado: (2019)

Screening and identification of MicroRNAs expressed in perirenal adipose tissue during rabbit growth
por: Wang, Guoze, et al.
Publicado: (2020)

Perirenal Adipose Tissue Inflammation: Novel Insights Linking Metabolic Dysfunction to Renal Diseases
por: Hammoud, Safaa H., et al.
Publicado: (2021)

Distribution, Morphological Characterization, and Resiniferatoxin-Susceptibility of Sensory Neurons That Innervate Rat Perirenal Adipose Tissue
por: Liu, Bo-Xun, et al.
Publicado: (2019)

Long term hypoxia during gestation alters perirenal adipose tissue gene expression in the lamb
por: Myers, Dean A., et al.
Publicado: (2020)

Increased oxidative stress, inflammation and fibrosis in perirenal adipose tissue of patients with cortisol-producing adenoma
por: Wu, Chunyan, et al.
Publicado: (2019)

Perirenal Adipose Tissue from Healthy Donor: Characteristics and Promise as Potential Therapeutic Cell Source
por: Lee, Eun Hye, et al.
Publicado: (2021)

Sexual dimorphic gene expression profile of perirenal adipose tissue in ovine fetuses with growth restriction
por: Blomberg, Jack, et al.
Publicado: (2023)

Perirenal Fluid Collection after Kidney Transplantation
por: Kim, Min Jee, et al.
Publicado: (2012)

Irisin and Cardiometabolic Disorders in Obesity: A Systematic Review
por: Pinho-Jr, Jorge da Silva, et al.
Publicado: (2023)

FSTL3 is highly expressed in adipose tissue of individuals with overweight or obesity and is associated with inflammation
por: Li, Xiaoya, et al.
Publicado: (2022)

Angiogenesis in adipose tissue and obesity
por: Corvera, Silvia, et al.
Publicado: (2022)

Transcriptomic Analysis Reveals the Protective Effects of Empagliflozin on Lipid Metabolism in Nonalcoholic Fatty Liver Disease
por: Ma, Yuting, et al.
Publicado: (2021)

Perirenal Lymphangiomatosis
por: Jeon, Tae Gyeong, et al.
Publicado: (2014)

Perirenal Abscess
por: Sumner, F. W.
Publicado: (1910)

Gene coexpression network analysis reveals perirenal adipose tissue as an important target of prenatal malnutrition in sheep
por: Ahmad, Sharmila, et al.
Publicado: (2023)

Screening and Identification of Differentially Expressed and Adipose Growth-Related Protein-Coding Genes During the Deposition of Perirenal Adipose Tissue in Rabbits
por: Wang, Guoze, et al.
Publicado: (2020)

Effects of the Myokine Irisin on Stromal Cells from Swine Adipose Tissue
por: Basini, Giuseppina, et al.
Publicado: (2022)

Markers of adipose tissue hypoxia are elevated in subcutaneous adipose tissue of severely obese patients with obesity hypoventilation syndrome but not in the moderately obese
por: Todorčević, Marijana, et al.
Publicado: (2021)

Ipragliflozin Ameliorates Diabetic Nephropathy Associated with Perirenal Adipose Expansion in Mice
por: Okuma, Hideyuki, et al.
Publicado: (2021)

Association of Serum Irisin with Metabolic Syndrome in Obese Chinese Adults
por: Yan, Bing, et al.
Publicado: (2014)

Irisin: A Hope in Understanding and Managing Obesity and Metabolic Syndrome
por: Arhire, Lidia I., et al.
Publicado: (2019)

Irisin as a Novel Biomarker of Subclinical Atherosclerosis in Severe Obesity
por: Carmona-Maurici, Júlia, et al.
Publicado: (2023)

Irisin improves adiposity and exercise tolerance in a rat model of postmenopausal obesity through enhancing adipo-myocyte thermogenesis
por: Gheit, Rehab E. Abo El, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qf6bgije0kg1v3ihjepofphuos