Single-cell spatial proteomic imaging for human neuropathology

ABSTRACT: Neurodegenerative disorders are characterized by phenotypic changes and hallmark proteopathies. Quantifying these in archival human brain tissues remains indispensable for validating animal models and understanding disease mechanisms. We present a framework for nanometer-scale, spatial pro...

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Detalles Bibliográficos
Autores principales: Vijayaragavan, Kausalia, Cannon, Bryan J., Tebaykin, Dmitry, Bossé, Marc, Baranski, Alex, Oliveria, J. P., Bukhari, Syed A., Mrdjen, Dunja, Corces, M. Ryan, McCaffrey, Erin F., Greenwald, Noah F., Sigal, Yari, Marquez, Diana, Khair, Zumana, Bruce, Trevor, Goldston, Mako, Bharadwaj, Anusha, Montine, Kathleen S., Angelo, R. Michael, Montine, Thomas J., Bendall, Sean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636771/
https://www.ncbi.nlm.nih.gov/pubmed/36333818
http://dx.doi.org/10.1186/s40478-022-01465-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636771/
https://www.ncbi.nlm.nih.gov/pubmed/36333818
http://dx.doi.org/10.1186/s40478-022-01465-x

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