JMJD4-demethylated RIG-I prevents hepatic steatosis and carcinogenesis

BACKGROUND: Hepatocarcinogenesis is driven by necroinflammation or metabolic disorders, and the underlying mechanisms remain largely elusive. We previously found that retinoic acid-inducible gene-I (RIG-I), a sensor for recognizing RNA virus in innate immune cells, is mainly expressed by parenchymal...

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Detalles Bibliográficos
Autores principales: Li, Zhenyang, Zhou, Ye, Jia, Kaiwei, Yang, Yingyun, Zhang, Liyuan, Wang, Suyuan, Dong, Yue, Wang, Mu, Li, Yunhui, Lu, Shan, Zhang, Wannian, Zhang, Luxin, Fan, Yiwen, Zhang, Dingji, Li, Nan, Yu, Yizhi, Cao, Xuetao, Hou, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636772/
https://www.ncbi.nlm.nih.gov/pubmed/36333807
http://dx.doi.org/10.1186/s13045-022-01381-6

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