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Cholesterol efflux regulator ABCA1 exerts protective role against high shear stress-induced injury of HBMECs via regulating PI3K/Akt/eNOS signaling
BACKGROUND: In brain, microvascular endothelial cells are exposed to various forces, including shear stress (SS). However, little is known about the effects of high shear stress (HSS) on human brain microvascular endothelial cells (HBMECs) and the underlying mechanism. The cholesterol efflux regulat...
Autores principales: | Li, Zhe, Li, Jia-Nan, Li, Qiang, Liu, Chun, Zhou, Lin-Hua, Zhang, Qi, Xu, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636808/ https://www.ncbi.nlm.nih.gov/pubmed/36335301 http://dx.doi.org/10.1186/s12868-022-00748-2 |
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