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Cholesterol efflux regulator ABCA1 exerts protective role against high shear stress-induced injury of HBMECs via regulating PI3K/Akt/eNOS signaling

BACKGROUND: In brain, microvascular endothelial cells are exposed to various forces, including shear stress (SS). However, little is known about the effects of high shear stress (HSS) on human brain microvascular endothelial cells (HBMECs) and the underlying mechanism. The cholesterol efflux regulat...

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Detalles Bibliográficos
Autores principales: Li, Zhe, Li, Jia-Nan, Li, Qiang, Liu, Chun, Zhou, Lin-Hua, Zhang, Qi, Xu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636808/
https://www.ncbi.nlm.nih.gov/pubmed/36335301
http://dx.doi.org/10.1186/s12868-022-00748-2

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