Targeted OUM1/PTPRZ1 silencing and synergetic CDT/enhanced chemical therapy toward uveal melanoma based on a dual-modal imaging-guided manganese metal–organic framework nanoparticles

Metastasis and chemical resistance are the most serious problems in the treatment of highly aggressive uveal melanoma (UM). The newly identified lncRNA OUM1 is overexpressed in UM, functions as a catalyst and regulates protein tyrosine phosphatase (PTP) activity by binding to PTP receptor type Z1 (P...

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Detalles Bibliográficos
Autores principales: Li, Yue, Li, Fang, Pan, Hui, Huang, Xiaolin, Yu, Jie, Liu, Xueru, Zhang, Qinghao, Xiao, Caiwen, Zhang, He, Zhang, Leilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636818/
https://www.ncbi.nlm.nih.gov/pubmed/36335349
http://dx.doi.org/10.1186/s12951-022-01643-y

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