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Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP
Conformational changes in voltage-sensing domains (VSDs) are driven by the transmembrane electric field acting on the protein charges. Yet, the overall energetics and detailed mechanism of this process are not fully understood. Here, we determined free energy and displacement charge landscapes as we...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636939/ https://www.ncbi.nlm.nih.gov/pubmed/36279472 http://dx.doi.org/10.1073/pnas.2206649119 |