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Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP

Conformational changes in voltage-sensing domains (VSDs) are driven by the transmembrane electric field acting on the protein charges. Yet, the overall energetics and detailed mechanism of this process are not fully understood. Here, we determined free energy and displacement charge landscapes as we...

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Detalles Bibliográficos
Autores principales:	Shen, Rong, Meng, Yilin, Roux, Benoît, Perozo, Eduardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636939/ https://www.ncbi.nlm.nih.gov/pubmed/36279472 http://dx.doi.org/10.1073/pnas.2206649119

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