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Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis

Uterine leiomyomas (UL) are benign tumors that arise in the myometrial layer of the uterus. The standard treatment option for UL is hysterectomy, although hormonal therapies, such as selective progesterone receptor modulators, are often used as temporary treatment options to reduce symptoms or to sl...

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Detalles Bibliográficos
Autores principales: Cloud, Ashley S., Koohestani, Faezeh, McWilliams, Michelle M., Ganeshkumar, Sornakala, Gunewardena, Sumedha, Graham, Amanda, Nothnick, Warren B., Chennathukuzhi, Vargheese M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636955/
https://www.ncbi.nlm.nih.gov/pubmed/36282915
http://dx.doi.org/10.1073/pnas.2205524119