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Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis
Uterine leiomyomas (UL) are benign tumors that arise in the myometrial layer of the uterus. The standard treatment option for UL is hysterectomy, although hormonal therapies, such as selective progesterone receptor modulators, are often used as temporary treatment options to reduce symptoms or to sl...
Autores principales: | Cloud, Ashley S., Koohestani, Faezeh, McWilliams, Michelle M., Ganeshkumar, Sornakala, Gunewardena, Sumedha, Graham, Amanda, Nothnick, Warren B., Chennathukuzhi, Vargheese M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636955/ https://www.ncbi.nlm.nih.gov/pubmed/36282915 http://dx.doi.org/10.1073/pnas.2205524119 |
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