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Epigenetic analysis of cell-free DNA by fragmentomic profiling

Cell-free DNA (cfDNA) fragmentation patterns contain important molecular information linked to tissues of origin. We explored the possibility of using fragmentation patterns to predict cytosine-phosphate-guanine (CpG) methylation of cfDNA, obviating the use of bisulfite treatment and associated risk...

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Detalles Bibliográficos
Autores principales:	Zhou, Qing, Kang, Guannan, Jiang, Peiyong, Qiao, Rong, Lam, W. K. Jacky, Yu, Stephanie C. Y., Ma, Mary-Jane L., Ji, Lu, Cheng, Suk Hang, Gai, Wanxia, Peng, Wenlei, Shang, Huimin, Chan, Rebecca W. Y., Chan, Stephen L., Wong, Grace L. H., Hiraki, Linda T., Volpi, Stefano, Wong, Vincent W. S., Wong, John, Chiu, Rossa W. K., Chan, K. C. Allen, Lo, Y. M. Dennis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636966/ https://www.ncbi.nlm.nih.gov/pubmed/36288287 http://dx.doi.org/10.1073/pnas.2209852119

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