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Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR
Transitioning from pluripotency to differentiated cell fates is fundamental to both embryonic development and adult tissue homeostasis. Improving our understanding of this transition would facilitate our ability to manipulate pluripotent cells into tissues for therapeutic use. Here, we show that mem...
Autores principales: | Sempou, Emily, Kostiuk, Valentyna, Zhu, Jie, Cecilia Guerra, M., Tyan, Leonid, Hwang, Woong, Camacho-Aguilar, Elena, Caplan, Michael J., Zenisek, David, Warmflash, Aryeh, Owens, Nick D. L., Khokha, Mustafa K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637099/ https://www.ncbi.nlm.nih.gov/pubmed/36335122 http://dx.doi.org/10.1038/s41467-022-34363-w |
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