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Androgen deprivation restores ARHGEF2 to promote neuroendocrine differentiation of prostate cancer

Androgen receptor (AR) plays an important role in the progression of prostate cancer and has been targeted by castration or AR-antagonists. The emergence of castration-resistant prostate cancer (CRPC) after androgen deprivation therapy (ADT) is inevitable. However, it is not entirely clear how ADT f...

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Detalles Bibliográficos
Autores principales: Chen, Xuanrong, Shao, Yi, Wei, Wanqing, Zhu, Shimiao, Li, Yang, Chen, Yutong, Li, Hanling, Tian, Hao, Sun, Guijiang, Niu, Yuanjie, Shang, Zhiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637107/
https://www.ncbi.nlm.nih.gov/pubmed/36335093
http://dx.doi.org/10.1038/s41419-022-05366-8

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