The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis

The assembly of mammalian SWI/SNF chromatin remodeling complexes is developmentally programed, and loss/mutations of SWI/SNF subunits alter the levels of other components through proteolysis, causing cancers. Here, we show that mouse Lsd1/Kdm1a deletion causes dramatic dissolution of SWI/SNF complex...

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Detalles Bibliográficos
Autores principales: Guo, Pengfei, Hoang, Nam, Sanchez, Joseph, Zhang, Elaine H., Rajawasam, Keshari, Trinidad, Kristiana, Sun, Hong, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637158/
https://www.ncbi.nlm.nih.gov/pubmed/36335117
http://dx.doi.org/10.1038/s41467-022-34348-9

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