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Acute poisoning in children in Ethiopia: a cross-sectional study

Acute poisoning is a global pediatric emergency problem. However, a wide variation in patterns of acute poisoning and associated factors across different geographical regions was stated. As a result, our research focused on the investigation of acute poisoning in children. An Institutional-based Ret...

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Autores principales: Molla, Yalew Melkamu, Belachew, Kassahun Denekew, Ayehu, Gashaw Walle, Teshome, Assefa Agegnehu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637174/
https://www.ncbi.nlm.nih.gov/pubmed/36335242
http://dx.doi.org/10.1038/s41598-022-23193-x
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author Molla, Yalew Melkamu
Belachew, Kassahun Denekew
Ayehu, Gashaw Walle
Teshome, Assefa Agegnehu
author_facet Molla, Yalew Melkamu
Belachew, Kassahun Denekew
Ayehu, Gashaw Walle
Teshome, Assefa Agegnehu
author_sort Molla, Yalew Melkamu
collection PubMed
description Acute poisoning is a global pediatric emergency problem. However, a wide variation in patterns of acute poisoning and associated factors across different geographical regions was stated. As a result, our research focused on the investigation of acute poisoning in children. An Institutional-based Retrospective study design was conducted at the University of Gondar comprehensive specialized hospital from October 2016 to October 2020. The analysis of the data was performed via SPSS Version 25. Furthermore, multiple logistic regression analysis was recruited. A P-value ≤ 0.05 was declared as statistically significant. Our study's prevalence of acute poisoning was 82/5489 (1.5%). 53 (64.6%) of patients were males. Of the total patients who had the diagnosis of poisoning, 54 (65.9%) came from rural areas. Venom was the most frequent offending agent (26.8%) and oral ingestion was the most common route of exposure (70.7%). Of the total patients who had the diagnosis of poisoning, 54 (65.9%) came from rural areas. Venom was the most frequent offending agent (26.8%), followed by insecticides (organophosphates) (21.5%). Accidental poisoning was the most common mode of poisoning more often than intentional (75.6–24.4%). The digestive tract (oral ingestion) (69.5%) was the commonest route of poisoning, followed by the cutaneous (skin bite) (24.4%). Death was three times more likely in the rural population than in urban residents [AOR 2.9 (1.21–13.7); P value 0.046]. Appropriate emergency care is the mainstay of the supportive management protocol for childhood poisoning.
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spelling pubmed-96371742022-11-07 Acute poisoning in children in Ethiopia: a cross-sectional study Molla, Yalew Melkamu Belachew, Kassahun Denekew Ayehu, Gashaw Walle Teshome, Assefa Agegnehu Sci Rep Article Acute poisoning is a global pediatric emergency problem. However, a wide variation in patterns of acute poisoning and associated factors across different geographical regions was stated. As a result, our research focused on the investigation of acute poisoning in children. An Institutional-based Retrospective study design was conducted at the University of Gondar comprehensive specialized hospital from October 2016 to October 2020. The analysis of the data was performed via SPSS Version 25. Furthermore, multiple logistic regression analysis was recruited. A P-value ≤ 0.05 was declared as statistically significant. Our study's prevalence of acute poisoning was 82/5489 (1.5%). 53 (64.6%) of patients were males. Of the total patients who had the diagnosis of poisoning, 54 (65.9%) came from rural areas. Venom was the most frequent offending agent (26.8%) and oral ingestion was the most common route of exposure (70.7%). Of the total patients who had the diagnosis of poisoning, 54 (65.9%) came from rural areas. Venom was the most frequent offending agent (26.8%), followed by insecticides (organophosphates) (21.5%). Accidental poisoning was the most common mode of poisoning more often than intentional (75.6–24.4%). The digestive tract (oral ingestion) (69.5%) was the commonest route of poisoning, followed by the cutaneous (skin bite) (24.4%). Death was three times more likely in the rural population than in urban residents [AOR 2.9 (1.21–13.7); P value 0.046]. Appropriate emergency care is the mainstay of the supportive management protocol for childhood poisoning. Nature Publishing Group UK 2022-11-05 /pmc/articles/PMC9637174/ /pubmed/36335242 http://dx.doi.org/10.1038/s41598-022-23193-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Molla, Yalew Melkamu
Belachew, Kassahun Denekew
Ayehu, Gashaw Walle
Teshome, Assefa Agegnehu
Acute poisoning in children in Ethiopia: a cross-sectional study
title Acute poisoning in children in Ethiopia: a cross-sectional study
title_full Acute poisoning in children in Ethiopia: a cross-sectional study
title_fullStr Acute poisoning in children in Ethiopia: a cross-sectional study
title_full_unstemmed Acute poisoning in children in Ethiopia: a cross-sectional study
title_short Acute poisoning in children in Ethiopia: a cross-sectional study
title_sort acute poisoning in children in ethiopia: a cross-sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637174/
https://www.ncbi.nlm.nih.gov/pubmed/36335242
http://dx.doi.org/10.1038/s41598-022-23193-x
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