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In situ Preparation of a Phospholipid Gel Co-Loaded with Methotrexate and Dexamethasone for Synergistic Rheumatoid Arthritis Treatment
BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by arthrocele, cartilage damage and disability. Although several anti-RA drugs have been developed for long-term treatment, they require frequent local injection and lead to multiple adverse effects such as osteoporo...
Autores principales: | Pu, Qian, Wang, Kaiyue, Peng, Bigeng, Chen, Kexin, Gong, Tao, Liu, Fu, Yang, Qin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637340/ https://www.ncbi.nlm.nih.gov/pubmed/36348765 http://dx.doi.org/10.2147/IJN.S384772 |
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