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Ketosis-Prone Type 2 Diabetes Mellitus: An Unusual Presentation

Ketosis-prone type 2 diabetes is a form of diabetes that usually presents with diabetic ketoacidosis (DKA) in patients who are not insulin dependent. It is commonly seen in African, African American, and Hispanic populations. Although the pathogenesis is not fully understood yet, it is believed to b...

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Autores principales: Makahleh, Lana, Othman, Ahmad, Vedantam, Venkata, Vedantam, Neethu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637373/
https://www.ncbi.nlm.nih.gov/pubmed/36348924
http://dx.doi.org/10.7759/cureus.30031
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author Makahleh, Lana
Othman, Ahmad
Vedantam, Venkata
Vedantam, Neethu
author_facet Makahleh, Lana
Othman, Ahmad
Vedantam, Venkata
Vedantam, Neethu
author_sort Makahleh, Lana
collection PubMed
description Ketosis-prone type 2 diabetes is a form of diabetes that usually presents with diabetic ketoacidosis (DKA) in patients who are not insulin dependent. It is commonly seen in African, African American, and Hispanic populations. Although the pathogenesis is not fully understood yet, it is believed to be caused by stress-induced reversible beta-cell and alpha-cell dysfunction in the pancreas. Here, we describe the case of an 80-year-old white female with well-controlled type 2 diabetes mellitus who had unexplained DKA in the setting of a urinary tract infection. The patient’s DKA resolved after administering appropriate therapy, and she did not require treatment with insulin on discharge.
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spelling pubmed-96373732022-11-07 Ketosis-Prone Type 2 Diabetes Mellitus: An Unusual Presentation Makahleh, Lana Othman, Ahmad Vedantam, Venkata Vedantam, Neethu Cureus Endocrinology/Diabetes/Metabolism Ketosis-prone type 2 diabetes is a form of diabetes that usually presents with diabetic ketoacidosis (DKA) in patients who are not insulin dependent. It is commonly seen in African, African American, and Hispanic populations. Although the pathogenesis is not fully understood yet, it is believed to be caused by stress-induced reversible beta-cell and alpha-cell dysfunction in the pancreas. Here, we describe the case of an 80-year-old white female with well-controlled type 2 diabetes mellitus who had unexplained DKA in the setting of a urinary tract infection. The patient’s DKA resolved after administering appropriate therapy, and she did not require treatment with insulin on discharge. Cureus 2022-10-07 /pmc/articles/PMC9637373/ /pubmed/36348924 http://dx.doi.org/10.7759/cureus.30031 Text en Copyright © 2022, Makahleh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Makahleh, Lana
Othman, Ahmad
Vedantam, Venkata
Vedantam, Neethu
Ketosis-Prone Type 2 Diabetes Mellitus: An Unusual Presentation
title Ketosis-Prone Type 2 Diabetes Mellitus: An Unusual Presentation
title_full Ketosis-Prone Type 2 Diabetes Mellitus: An Unusual Presentation
title_fullStr Ketosis-Prone Type 2 Diabetes Mellitus: An Unusual Presentation
title_full_unstemmed Ketosis-Prone Type 2 Diabetes Mellitus: An Unusual Presentation
title_short Ketosis-Prone Type 2 Diabetes Mellitus: An Unusual Presentation
title_sort ketosis-prone type 2 diabetes mellitus: an unusual presentation
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637373/
https://www.ncbi.nlm.nih.gov/pubmed/36348924
http://dx.doi.org/10.7759/cureus.30031
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