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IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
Signaling through innate immune receptors such as the Toll-like receptor (TLR)/interleukin-1 receptor (IL-1R) superfamily proceeds via the assembly of large membrane-proximal complexes or “signalosomes.” Although structurally distinct, the IL-17 receptor family triggers cellular responses that are t...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637376/ https://www.ncbi.nlm.nih.gov/pubmed/36260993 http://dx.doi.org/10.1016/j.celrep.2022.111489 |