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IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling

Signaling through innate immune receptors such as the Toll-like receptor (TLR)/interleukin-1 receptor (IL-1R) superfamily proceeds via the assembly of large membrane-proximal complexes or “signalosomes.” Although structurally distinct, the IL-17 receptor family triggers cellular responses that are t...

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Detalles Bibliográficos
Autores principales:	Goepfert, Arnaud, Barske, Carmen, Lehmann, Sylvie, Wirth, Emmanuelle, Willemsen, Joschka, Gudjonsson, Johann E., Ward, Nicole L., Sarkar, Mrinal K., Hemmig, René, Kolbinger, Frank, Rondeau, Jean-Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637376/ https://www.ncbi.nlm.nih.gov/pubmed/36260993 http://dx.doi.org/10.1016/j.celrep.2022.111489

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