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Intramural Jejunal Hematoma Causing Intermittent Bowel Obstruction—A Rare Manifestation of Warfarin Toxicity

Patients with thromboembolic disorders are commonly on anticoagulants; hence, they are susceptible to bleeding episodes such as ecchymosis, gingival, subconjunctival bleeding, and rarely can have intramural hematoma of small bowel causing patient to present with intestinal obstruction. It is a rare...

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Autores principales: Patil, Arun S., Shriya, Shriya, Dhimole, Nikhil, More, Jalbaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers, Inc. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637411/
https://www.ncbi.nlm.nih.gov/pubmed/36349086
http://dx.doi.org/10.1055/s-0042-1755223
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author Patil, Arun S.
Shriya, Shriya
Dhimole, Nikhil
More, Jalbaji
author_facet Patil, Arun S.
Shriya, Shriya
Dhimole, Nikhil
More, Jalbaji
author_sort Patil, Arun S.
collection PubMed
description Patients with thromboembolic disorders are commonly on anticoagulants; hence, they are susceptible to bleeding episodes such as ecchymosis, gingival, subconjunctival bleeding, and rarely can have intramural hematoma of small bowel causing patient to present with intestinal obstruction. It is a rare cause of mechanical bowel obstruction requiring a nonsurgical management. Our patient was a 55-year-old male, a known case of thromboembolism on warfarin medication, presented with abdominal pain and vomiting. Patient's laboratory reports reflected anemia and deranged coagulation profile with prothrombin time and international normalized ratio, both being elevated. Intramural hematoma of jejunum was diagnosed by abdominal contrast-enhanced computed tomography. Conservative management was done, warfarin was stopped and vitamin K was administered. Patient received fresh frozen plasma and packed cell blood. It is important to suspect warfarin toxicity in patients on the medication who come with such presentation to avoid surgical management, which could be catastrophic due to excessive bleeding. It is important for regular monitoring of coagulation profile of such patients and to reduce prescribing other medications that can interact with warfarin. It is worth noting that novel oral anticoagulants, such as dabigatran and rivaroxaban, are associated with fewer side effects and do not require close laboratory monitoring.
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spelling pubmed-96374112022-11-07 Intramural Jejunal Hematoma Causing Intermittent Bowel Obstruction—A Rare Manifestation of Warfarin Toxicity Patil, Arun S. Shriya, Shriya Dhimole, Nikhil More, Jalbaji Surg J (N Y) Patients with thromboembolic disorders are commonly on anticoagulants; hence, they are susceptible to bleeding episodes such as ecchymosis, gingival, subconjunctival bleeding, and rarely can have intramural hematoma of small bowel causing patient to present with intestinal obstruction. It is a rare cause of mechanical bowel obstruction requiring a nonsurgical management. Our patient was a 55-year-old male, a known case of thromboembolism on warfarin medication, presented with abdominal pain and vomiting. Patient's laboratory reports reflected anemia and deranged coagulation profile with prothrombin time and international normalized ratio, both being elevated. Intramural hematoma of jejunum was diagnosed by abdominal contrast-enhanced computed tomography. Conservative management was done, warfarin was stopped and vitamin K was administered. Patient received fresh frozen plasma and packed cell blood. It is important to suspect warfarin toxicity in patients on the medication who come with such presentation to avoid surgical management, which could be catastrophic due to excessive bleeding. It is important for regular monitoring of coagulation profile of such patients and to reduce prescribing other medications that can interact with warfarin. It is worth noting that novel oral anticoagulants, such as dabigatran and rivaroxaban, are associated with fewer side effects and do not require close laboratory monitoring. Thieme Medical Publishers, Inc. 2022-11-06 /pmc/articles/PMC9637411/ /pubmed/36349086 http://dx.doi.org/10.1055/s-0042-1755223 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Patil, Arun S.
Shriya, Shriya
Dhimole, Nikhil
More, Jalbaji
Intramural Jejunal Hematoma Causing Intermittent Bowel Obstruction—A Rare Manifestation of Warfarin Toxicity
title Intramural Jejunal Hematoma Causing Intermittent Bowel Obstruction—A Rare Manifestation of Warfarin Toxicity
title_full Intramural Jejunal Hematoma Causing Intermittent Bowel Obstruction—A Rare Manifestation of Warfarin Toxicity
title_fullStr Intramural Jejunal Hematoma Causing Intermittent Bowel Obstruction—A Rare Manifestation of Warfarin Toxicity
title_full_unstemmed Intramural Jejunal Hematoma Causing Intermittent Bowel Obstruction—A Rare Manifestation of Warfarin Toxicity
title_short Intramural Jejunal Hematoma Causing Intermittent Bowel Obstruction—A Rare Manifestation of Warfarin Toxicity
title_sort intramural jejunal hematoma causing intermittent bowel obstruction—a rare manifestation of warfarin toxicity
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637411/
https://www.ncbi.nlm.nih.gov/pubmed/36349086
http://dx.doi.org/10.1055/s-0042-1755223
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