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Correlation of Morphological Findings of Endometrium With Concerned Hormone Levels in Patients With Abnormal Uterine Bleeding: A Narrative Review

Abnormal uterine bleeding (AUB) is a distressing menstrual condition that continues to be one of the most common rationales for hysterectomy in underdeveloped countries. It can be either focal (breakthrough bleeding) or diffuse (bleeding throughout the body) (withdrawal bleeding). AUB has a negative...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Tanvi T, Hiwale, K.M., Vagha, Sunita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637461/
https://www.ncbi.nlm.nih.gov/pubmed/36381922
http://dx.doi.org/10.7759/cureus.30063
Descripción
Sumario:Abnormal uterine bleeding (AUB) is a distressing menstrual condition that continues to be one of the most common rationales for hysterectomy in underdeveloped countries. It can be either focal (breakthrough bleeding) or diffuse (bleeding throughout the body) (withdrawal bleeding). AUB has a negative impact on a female's physical, social, and emotional well-being. It is caused by chronic endometritis, micro erosions, or vascular fragility caused by micro-vessel structural anomalies. Polyps, submucosal leiomyoma, atrophy, and cancer can all produce endometritis and micro erosions in otherwise healthy endometrium (organic causes). In hyperplasia and endometrial cancers, especially type I, estrogen and progesterone hormones are also expressed. The level of these hormones gives prognostic information. They also provide amenability to hormonal therapy. Hormonal imbalance is the main component involved in the pathogenesis of dysfunctional uterine bleeding (DUB).