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GRWR Correlates with the Metabolism of Tacrolimus after Pediatric Living Donor Liver Transplantation According to Donor CYP3A5 Polymorphism

OBJECTIVES: Tacrolimus is characterized by high pharmacokinetic variability in combination with a narrow therapeutic range. However, influence of donor CYP3A5 genotype and graft-to-recipient body weight ratio (GRWR) on tacrolimus' pharmacokinetics after pediatric living donor liver transplantat...

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Detalles Bibliográficos
Autores principales: Wan, Ping, Hou, Yuchen, Qiu, Bijun, Feng, Mingxuan, Yang, Taihua, Luo, Yi, Xia, Lei, Chen, Xiaosong, Zhang, Jianjun, Xue, Feng, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637468/
https://www.ncbi.nlm.nih.gov/pubmed/36349313
http://dx.doi.org/10.1155/2022/7647754