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The effect of rapamycin and its analogues on age-related musculoskeletal diseases: a systematic review

BACKGROUND: Preclinical studies have shown a therapeutic role of the mechanistic/mammalian target of rapamycin complex 1 (mTORC1) inhibition with rapamycin and its analogues (rapalogues) on several age-related musculoskeletal disorders (MSKD). However, the applicability to humans of these findings i...

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Detalles Bibliográficos
Autores principales: Lin, Hong, Salech, Felipe, Lim, Anthony, Vogrin, Sara, Duque, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637607/
https://www.ncbi.nlm.nih.gov/pubmed/35861940
http://dx.doi.org/10.1007/s40520-022-02190-0

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