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Aging hampers neutrophil extracellular traps (NETs) efficacy

BACKGROUND: NETosis is a neutrophil-mediated defense mechanism during which DNA and enzymes are extruded forming a network (NETs) trapping and killing different pathogens. NETosis is reduced in both mice and humans during aging. AIMS: We explored the difference in the efficacy of NETs released in el...

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Detalles Bibliográficos
Autores principales: Sabbatini, Maurizio, Bona, Elisa, Novello, Giorgia, Migliario, Mario, Renò, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637667/
https://www.ncbi.nlm.nih.gov/pubmed/35920993
http://dx.doi.org/10.1007/s40520-022-02201-0