Aurora A–mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression

Cancer cells have distinctive demands for intermediates from glucose metabolism for biosynthesis and energy in different cell cycle phases. However, how cell cycle regulators and glycolytic enzymes coordinate to orchestrate the essential metabolic processes are still poorly characterized. Here, we r...

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Detalles Bibliográficos
Autores principales: Jiang, Ya, Wang, Ting, Sheng, Dandan, Han, Chaoqiang, Xu, Tian, Zhang, Peng, You, Weiyi, Fan, Weiwei, Zhang, Zhiyong, Jin, Tengchuan, Duan, Xiaotao, Yuan, Xiao, Liu, Xing, Zhang, Kaiguang, Ruan, Ke, Shi, Jue, Guo, Jing, Cheng, Aoxing, Yang, Zhenye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637814/
https://www.ncbi.nlm.nih.gov/pubmed/36198360
http://dx.doi.org/10.1016/j.jbc.2022.102561

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