Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells

Chimeric antigen receptor (CAR-) T cell therapy is a relatively new form of immunotherapy for hematological malignancies. Although patients are at increased risk of infection following CAR-T cell therapy, reports of fungal infections are scarce. We report a case of Scedosporium apiospermum infection...

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Autores principales: Falkenburg, Willem J.J., Jalink, Marit, Kersten, Marie José, Buil, Jochem B., van Dijk, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637851/
https://www.ncbi.nlm.nih.gov/pubmed/36353268
http://dx.doi.org/10.1016/j.mmcr.2022.10.002
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author Falkenburg, Willem J.J.
Jalink, Marit
Kersten, Marie José
Buil, Jochem B.
van Dijk, Karin
author_facet Falkenburg, Willem J.J.
Jalink, Marit
Kersten, Marie José
Buil, Jochem B.
van Dijk, Karin
author_sort Falkenburg, Willem J.J.
collection PubMed
description Chimeric antigen receptor (CAR-) T cell therapy is a relatively new form of immunotherapy for hematological malignancies. Although patients are at increased risk of infection following CAR-T cell therapy, reports of fungal infections are scarce. We report a case of Scedosporium apiospermum infection causing bursitis of the elbow in a lymphoma patient after treatment with CAR-T cells. The fungal bursitis relapsed under posaconazole treatment, but was cured after surgical extirpation of the bursa.
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spelling pubmed-96378512022-11-08 Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells Falkenburg, Willem J.J. Jalink, Marit Kersten, Marie José Buil, Jochem B. van Dijk, Karin Med Mycol Case Rep Case Report Chimeric antigen receptor (CAR-) T cell therapy is a relatively new form of immunotherapy for hematological malignancies. Although patients are at increased risk of infection following CAR-T cell therapy, reports of fungal infections are scarce. We report a case of Scedosporium apiospermum infection causing bursitis of the elbow in a lymphoma patient after treatment with CAR-T cells. The fungal bursitis relapsed under posaconazole treatment, but was cured after surgical extirpation of the bursa. Elsevier 2022-10-28 /pmc/articles/PMC9637851/ /pubmed/36353268 http://dx.doi.org/10.1016/j.mmcr.2022.10.002 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Falkenburg, Willem J.J.
Jalink, Marit
Kersten, Marie José
Buil, Jochem B.
van Dijk, Karin
Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells
title Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells
title_full Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells
title_fullStr Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells
title_full_unstemmed Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells
title_short Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells
title_sort olecranon bursitis caused by scedosporium apiospermum in a patient treated with car-t cells
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637851/
https://www.ncbi.nlm.nih.gov/pubmed/36353268
http://dx.doi.org/10.1016/j.mmcr.2022.10.002
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