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Cutaneous sporotrichoid leishmaniasis: An atypical case caused by Leishmania major

A 32 year-old male was referred in our institution for painless erythematous papules on the back of the right hand, treated by various local therapies with no noticeable benefits. On examination multiples inconspicuous nodules were identified 10 days after the onset of the primary lesion. Mycologica...

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Detalles Bibliográficos
Autores principales: Bassaid, Adila, Merad, Yassine, Ait Si Ali, Mohand Ouali, Djeridane, Assya, Bachi, Fatma, Adjmi-Hamoudi, Haiet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637879/
https://www.ncbi.nlm.nih.gov/pubmed/36353702
http://dx.doi.org/10.1016/j.idcr.2022.e01629
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author Bassaid, Adila
Merad, Yassine
Ait Si Ali, Mohand Ouali
Djeridane, Assya
Bachi, Fatma
Adjmi-Hamoudi, Haiet
author_facet Bassaid, Adila
Merad, Yassine
Ait Si Ali, Mohand Ouali
Djeridane, Assya
Bachi, Fatma
Adjmi-Hamoudi, Haiet
author_sort Bassaid, Adila
collection PubMed
description A 32 year-old male was referred in our institution for painless erythematous papules on the back of the right hand, treated by various local therapies with no noticeable benefits. On examination multiples inconspicuous nodules were identified 10 days after the onset of the primary lesion. Mycological examination was done to rule out sporotrichosis, then cutaneous leishmaniasis was retained by finding amastigotes forms, and Leishmania major agent was confirmed after culture on NNN medium followed by isoenzyme electrophoresis. Sporortrichoid leishmaniasis is a rare condition and usually due to extension of local leishmaniasis into the subcutaneous tissue via direct extension, bloodstream or lymphatics. The patient responded favorably to Meglumine antimoniate treatment. To our knowledge, sporotrichoid cutaneous leishmaniasis after an erythematous-papular onset has never been reported in Algeria, this clinical entity should be considered for an earlier diagnosis and specific therapy.
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spelling pubmed-96378792022-11-08 Cutaneous sporotrichoid leishmaniasis: An atypical case caused by Leishmania major Bassaid, Adila Merad, Yassine Ait Si Ali, Mohand Ouali Djeridane, Assya Bachi, Fatma Adjmi-Hamoudi, Haiet IDCases Case Report A 32 year-old male was referred in our institution for painless erythematous papules on the back of the right hand, treated by various local therapies with no noticeable benefits. On examination multiples inconspicuous nodules were identified 10 days after the onset of the primary lesion. Mycological examination was done to rule out sporotrichosis, then cutaneous leishmaniasis was retained by finding amastigotes forms, and Leishmania major agent was confirmed after culture on NNN medium followed by isoenzyme electrophoresis. Sporortrichoid leishmaniasis is a rare condition and usually due to extension of local leishmaniasis into the subcutaneous tissue via direct extension, bloodstream or lymphatics. The patient responded favorably to Meglumine antimoniate treatment. To our knowledge, sporotrichoid cutaneous leishmaniasis after an erythematous-papular onset has never been reported in Algeria, this clinical entity should be considered for an earlier diagnosis and specific therapy. Elsevier 2022-11-01 /pmc/articles/PMC9637879/ /pubmed/36353702 http://dx.doi.org/10.1016/j.idcr.2022.e01629 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Bassaid, Adila
Merad, Yassine
Ait Si Ali, Mohand Ouali
Djeridane, Assya
Bachi, Fatma
Adjmi-Hamoudi, Haiet
Cutaneous sporotrichoid leishmaniasis: An atypical case caused by Leishmania major
title Cutaneous sporotrichoid leishmaniasis: An atypical case caused by Leishmania major
title_full Cutaneous sporotrichoid leishmaniasis: An atypical case caused by Leishmania major
title_fullStr Cutaneous sporotrichoid leishmaniasis: An atypical case caused by Leishmania major
title_full_unstemmed Cutaneous sporotrichoid leishmaniasis: An atypical case caused by Leishmania major
title_short Cutaneous sporotrichoid leishmaniasis: An atypical case caused by Leishmania major
title_sort cutaneous sporotrichoid leishmaniasis: an atypical case caused by leishmania major
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637879/
https://www.ncbi.nlm.nih.gov/pubmed/36353702
http://dx.doi.org/10.1016/j.idcr.2022.e01629
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