Outer surface lipoproteins from the Lyme disease spirochete exploit the molecular switch mechanism of the complement protease C1s

Proteolytic cascades comprise several important physiological systems, including a primary arm of innate immunity called the complement cascade. To safeguard against complement-mediated attack, the etiologic agent of Lyme disease, Borreliella burgdorferi, produces numerous outer surface–localized li...

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Detalles Bibliográficos
Autores principales: Garrigues, Ryan J., Thomas, Sheila, Leong, John M., Garcia, Brandon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637899/
https://www.ncbi.nlm.nih.gov/pubmed/36183830
http://dx.doi.org/10.1016/j.jbc.2022.102557

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