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Inflammatory signaling on cytochrome P450-mediated drug metabolism in hepatocytes

Cytochrome P450 (CYP450) enzymes are membrane-bound blood proteins that are vital to drug detoxification, cell metabolism, and homeostasis. CYP450s belonging to CYP families 1–3 are responsible for nearly 80% of oxidative metabolism and complete elimination of approximately 50% of all common clinica...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaokang, Rao, Jiaoyu, Tan, Zhiyi, Xun, Tianrong, Zhao, Jingqian, Yang, Xixiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637984/ https://www.ncbi.nlm.nih.gov/pubmed/36353494 http://dx.doi.org/10.3389/fphar.2022.1043836

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