Markers for DNA damage are induced in the rat colon by the Alternaria toxin altertoxin-II, but not a complex extract of cultured Alternaria alternata

Mycotoxins produced by Alternaria spp. act genotoxic in cell-based studies, but data on their toxicity in vivo is scarce and urgently required for risk assessment. Thus, male Sprague-Dawley rats received single doses of a complex Alternaria toxin extract (CE; 50 mg/kg bw), altertoxin II (ATX-II; 0.2...

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Detalles Bibliográficos
Autores principales: Aichinger, Georg, Pahlke, Gudrun, Puntscher, Hannes, Groestlinger, Julia, Grabher, Stephanie, Braun, Dominik, Tillmann, Katharina, Plasenzotti, Roberto, Del Favero, Giorgia, Warth, Benedikt, Höger, Harald, Marko, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638006/
https://www.ncbi.nlm.nih.gov/pubmed/36353200
http://dx.doi.org/10.3389/ftox.2022.977147

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