Cargando…

The role of APTX4870 peptide in reducing cellular inflammatory responses by inhibiting Mycobacterium tuberculosis-derived mycolic acid-induced cytotoxicity

Tuberculosis is a serious zoonotic disease caused by Mycobacterium tuberculosis (M.tb) and the M.tb complex. Mycolic acid is an extracellular carbohydrate polymer produced, secreted, and accumulated outside the cells of various Mycobacterium tuberculosis strains. Mycolic acid produced by Mycobacteri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Xue, Jia, Wei, Feng, Gangning, Su, Yajing, Kang, Yuting, Zhang, Chen, Liu, Wenmiao, Lu, Zhidong, Xue, Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638010/ https://www.ncbi.nlm.nih.gov/pubmed/36353454 http://dx.doi.org/10.3389/fmicb.2022.993897

Ejemplares similares

N-acetylcysteine (NAC) Attenuating Apoptosis and Autophagy in RAW264.7 Cells in Response to Incubation with Mycolic Acid from Bovine Mycobacterium tuberculosis Complex
por: LIN, XUE, et al.
Publicado: (2020)

Controlling Extra- and Intramacrophagic Mycobacterium abscessus by Targeting Mycolic Acid Transport
por: Viljoen, Albertus, et al.
Publicado: (2017)

Identifying the Novel Inhibitors Against the Mycolic Acid Biosynthesis Pathway Target “mtFabH” of Mycobacterium tuberculosis
por: Kumar, Niranjan, et al.
Publicado: (2022)

Total Synthesis of a Mycolic Acid from Mycobacterium tuberculosis
por: Tahiri, Nabil, et al.
Publicado: (2020)

Lipidomics and genomics of Mycobacterium tuberculosis reveal lineage-specific trends in mycolic acid biosynthesis
por: Portevin, Damien, et al.
Publicado: (2014)

INHIBITION OF MYCOLIC ACID TRANSPORT ACROSS THE MYCOBACTERIUM TUBERCULOSIS PLASMA MEMBRANE
por: Grzegorzewicz, Anna E., et al.
Publicado: (2012)

Synthesis and Biological Aspects of Mycolic Acids: An Important Target Against Mycobacterium tuberculosis
por: de Souza, Marcus Vinícius Nora, et al.
Publicado: (2008)

Effect of an Oxadiazoline and a Lignan on Mycolic Acid Biosynthesis and Ultrastructural Changes of Mycobacterium tuberculosis
por: Baquero, Eduard, et al.
Publicado: (2011)

Lack of methoxy-mycolates characterizes the geographically restricted lineage 7 of Mycobacterium tuberculosis complex
por: Hailu, Elena, et al.
Publicado: (2023)

The role of TDP1 and APTX in mitochondrial DNA repair
por: Meagher, Martin, et al.
Publicado: (2014)

Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria
por: Ojha, Anil K, et al.
Publicado: (2008)

Interpreting Expression Data with Metabolic Flux Models: Predicting Mycobacterium tuberculosis Mycolic Acid Production
por: Colijn, Caroline, et al.
Publicado: (2009)

The Mycobacterium Tuberculosis FAS-II Dehydratases and Methyltransferases Define the Specificity of the Mycolic Acid Elongation Complexes
por: Cantaloube, Sylvain, et al.
Publicado: (2011)

Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis
por: Sambandan, Dhinakaran, et al.
Publicado: (2013)

Conformational Dynamics and Stability of Bilayers Formed by Mycolic Acids from the Mycobacterium tuberculosis Outer Membrane
por: Savintseva, Liana A., et al.
Publicado: (2023)

Revealing solvent-dependent folding behavior of mycolic acids from Mycobacterium tuberculosis by advanced simulation analysis
por: Groenewald, Wilma, et al.
Publicado: (2019)

Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease
por: Tumbale, Percy, et al.
Publicado: (2018)

A Novel APTX Variant and Ataxia with Oculomotor Apraxia Type 1
por: Manzoor, Humera, et al.
Publicado: (2017)

Identification of a Desaturase Involved in Mycolic Acid Biosynthesis in Mycobacterium smegmatis
por: Singh, Albel, et al.
Publicado: (2016)

Mycobacterium tuberculosis Proteins Involved in Mycolic Acid Synthesis and Transport Localize Dynamically to the Old Growing Pole and Septum
por: Carel, Clément, et al.
Publicado: (2014)

Mycolic acid-specific T cells protect against Mycobacterium tuberculosis infection in a humanized transgenic mouse model
por: Zhao, Jie, et al.
Publicado: (2015)

Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response
por: Rodel, Hylton E., et al.
Publicado: (2021)

Unveiling the Biosynthetic Pathway for Short Mycolic Acids in Nontuberculous Mycobacteria: Mycobacterium smegmatis MSMEG_4301 and Its Ortholog Mycobacterium abscessus MAB_1915 Are Essential for the Synthesis of α′-Mycolic Acids
por: Di Capua, Cecilia B., et al.
Publicado: (2022)

Structure–function relationships of the antigenicity of mycolic acids in tuberculosis patients
por: Beukes, Mervyn, et al.
Publicado: (2010)

Complete APTX deletion in a patient with ataxia with oculomotor apraxia type 1
por: van Minkelen, Rick, et al.
Publicado: (2015)

Identification of a novel mutation in the APTX gene associated with ataxia-oculomotor apraxia
por: Inlora, Jingga, et al.
Publicado: (2017)

The aceE involves in mycolic acid synthesis and biofilm formation in Mycobacterium smegmatis
por: Chen, Suting, et al.
Publicado: (2020)

Induction of Mycobacterium Tuberculosis Lipid-Specific T Cell Responses by Pulmonary Delivery of Mycolic Acid-Loaded Polymeric Micellar Nanocarriers
por: Shang, Shaobin, et al.
Publicado: (2018)

Rifampin- or Capreomycin-Induced Remodeling of the Mycobacterium smegmatis Mycolic Acid Layer Is Mitigated in Synergistic Combinations with Cationic Antimicrobial Peptides
por: Man, DeDe Kwun-Wai, et al.
Publicado: (2018)

Phylogenomic Reappraisal of Fatty Acid Biosynthesis, Mycolic Acid Biosynthesis and Clinical Relevance Among Members of the Genus Corynebacterium
por: Dover, Lynn G., et al.
Publicado: (2021)

The Antimalarial Mefloquine Shows Activity against Mycobacterium abscessus, Inhibiting Mycolic Acid Metabolism
por: Degiacomi, Giulia, et al.
Publicado: (2021)

Controlling of Mycobacterium by Natural Degradant-Combination Models for Sequestering Mycolic Acids in Karish Cheese
por: Hamad, Gamal, et al.
Publicado: (2022)

Editorial: Cellular and Molecular Mechanisms of Mycobacterium tuberculosis Virulence
por: Sun, Jianjun, et al.
Publicado: (2019)

Antimicrobial peptides as drugs with double response against Mycobacterium tuberculosis coinfections in lung cancer
por: Polinário, Giulia, et al.
Publicado: (2023)

Mycobacterium abscessus biofilms produce an extracellular matrix and have a distinct mycolic acid profile
por: Dokic, Anja, et al.
Publicado: (2021)

Slow mitochondrial repair of 5′-AMP renders mtDNA susceptible to damage in APTX deficient cells
por: Akbari, Mansour, et al.
Publicado: (2015)

APTX acts in DNA double-strand break repair in a manner distinct from XRCC4
por: Imamura, Rikiya, et al.
Publicado: (2023)

Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice
por: Shui, Guanghou, et al.
Publicado: (2012)

Induction of tumor-specific CD8(+) cytotoxic T lymphocytes from naïve human T cells by using Mycobacterium-derived mycolic acid and lipoarabinomannan-stimulated dendritic cells
por: Tomita, Yuji, et al.
Publicado: (2019)

Genomic characteristics of Mycobacterium tuberculosis isolates of cutaneous tuberculosis
por: Mei, You-Ming, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_t03hhf37lj1jn9kftre7sks8ic