PDGFRβ(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny

Hematopoietic stem cell (HSC) generation in the aorta-gonad-mesonephros region requires HSC specification signals from the surrounding microenvironment. In zebrafish, PDGF-B/PDGFRβ signaling controls hematopoietic stem/progenitor cell (HSPC) generation and is required in the HSC specification niche....

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Detalles Bibliográficos
Autores principales: Sá da Bandeira, Diana, Kilpatrick, Alastair Morris, Marques, Madalena, Gomez-Salazar, Mario, Ventura, Telma, Gonzalez, Zaniah Nashira, Stefancova, Dorota, Rossi, Fiona, Vermeren, Matthieu, Vink, Chris Sebastiaan, Beltran, Mariana, Henderson, Neil Cowan, Jung, Bongnam, van der Linden, Reinier, van de Werken, Harmen Jan George, van Ijcken, Wilfred F.J., Betsholtz, Christer, Forbes, Stuart John, Cuervo, Henar, Crisan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638014/
https://www.ncbi.nlm.nih.gov/pubmed/35858557
http://dx.doi.org/10.1016/j.celrep.2022.111114

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