Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

Many bacterial pathogens antagonize host defense responses by translocating effector proteins into cells. It remains an open question how those pathogens not encoding effectors counteract anti-bacterial immunity. Here, we show that Klebsiella pneumoniae exploits the evolutionary conserved innate pro...

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Detalles Bibliográficos
Autores principales: Feriotti, Claudia, Sá-Pessoa, Joana, Calderón-González, Ricardo, Gu, Lili, Morris, Brenda, Sugisawa, Ryoichi, Insua, Jose L., Carty, Michael, Dumigan, Amy, Ingram, Rebecca J., Kissenpfening, Adrien, Bowie, Andrew G., Bengoechea, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638020/
https://www.ncbi.nlm.nih.gov/pubmed/35947948
http://dx.doi.org/10.1016/j.celrep.2022.111167

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