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(1S,3R)-N-{(3S,10S,12S,13R,17R)-12-Hy­droxy-17-[(R)-5-hy­droxy­pentan-2-yl]-10,13-di­methyl­hexa­deca­hydro-1H-cyclo­penta­[a]phenanthren-3-yl}adamantane-1-carboxamide 0.25-hydrate

The title compound, C(35)H(57)NO(3)·0.25H(2)O, was synthesized from de­oxy­cholic acid followed by a protection, a Mitsonobu substitution, a Staudinger reduction, formation of an amide and final reduction in the lateral chain. The compound crystallizes in the P1 space group with four steroid mol­ecu...

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Detalles Bibliográficos
Autores principales: Campos Fernandez, Cristian, Procupez-Schtirbu, R., Soto-Tellini, V. H., Salazar, J. C., Jancik, Vojtech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638062/
https://www.ncbi.nlm.nih.gov/pubmed/36405850
http://dx.doi.org/10.1107/S2414314622009476

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