Melatonin ameliorates bleomycin-induced pulmonary fibrosis via activating NRF2 and inhibiting galectin-3 expression

Pulmonary fibrosis (PF) is a chronic interstitial lung disease with no effective therapies. Galectin-3 (Gal-3), a marker of oxidative stress, plays a key role in the pathogenesis of PF. Fibroblast-myofibroblast differentiation (FMD) is an important source of fibrotic cells in PF. Previous studies sh...

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Detalles Bibliográficos
Autores principales: Lan, Yue-jiao, Cheng, Ming-han, Ji, Hui-min, Bi, Yu-qian, Han, Yong-yue, Yang, Chong-yang, Gu, Xuan, Gao, Jian, Dong, Hong-liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638373/
https://www.ncbi.nlm.nih.gov/pubmed/36333557
http://dx.doi.org/10.1038/s41401-022-01018-x

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