Bioinformatics Approaches to Predict Mutation Effects in the Binding Site of the Proangiogenic Molecule CD93

The transmembrane glycoprotein CD93 has been identified as a potential new target to inhibit tumor angiogenesis. Recently, Multimerin-2 (MMRN2), a pan-endothelial extracellular matrix protein, has been identified as a ligand for CD93, but the interaction mechanism between these two proteins is yet t...

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Detalles Bibliográficos
Autores principales: Cicaloni, Vittoria, Karmakar, Malancha, Frusciante, Luisa, Pettini, Francesco, Visibelli, Anna, Orlandini, Maurizio, Galvagni, Federico, Mongiat, Maurizio, Silk, Michael, Nardi, Federica, Ascher, David, Santucci, Annalisa, Spiga, Ottavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638713/
https://www.ncbi.nlm.nih.gov/pubmed/36353214
http://dx.doi.org/10.3389/fbinf.2022.891553

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