Cargando…

Combined targeting of KRT23 and NCCRP1 as a potential novel therapeutic approach for the treatment of triple-negative breast cancer

BACKGROUND: Breast cancers characterized by triple-negative status tend to be more malignant and have a poorer prognosis. A risk model for predicting breast cancer risk should be developed. METHODS: We obtained gene expression and clinical characteristics data using the Clinical Proteomic Tumor Anal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Jian, Qian, Weiwei, Huang, Cuiliu, Mai, Cunjun, Lai, Yimei, Lin, Zhiqin, Lai, Guie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638800/ https://www.ncbi.nlm.nih.gov/pubmed/36353580 http://dx.doi.org/10.21037/gs-22-486

Ejemplares similares

Interference KRT17 reverses doxorubicin resistance in triple-negative breast cancer cells by Wnt/β-catenin signaling pathway
por: Wu, Liqiong, et al.
Publicado: (2023)

Analysis of KRT1, KRT10, KRT19, TP53 and MMP9 expression in pediatric and adult cholesteatoma
por: Palkó, Enikő, et al.
Publicado: (2018)

Keratin23 (KRT23) Knockdown Decreases Proliferation and Affects the DNA Damage Response of Colon Cancer Cells
por: Birkenkamp-Demtröder, Karin, et al.
Publicado: (2013)

Transcriptome Analysis Reveals the Immune Infiltration Profiles in Cervical Cancer and Identifies KRT23 as an Immunotherapeutic Target
por: Li, Xia, et al.
Publicado: (2022)

Identification of presumed pathogenic KRT3 and KRT12 gene mutations associated with Meesmann corneal dystrophy
por: Chen, Judy L., et al.
Publicado: (2015)

KRT8 and KRT19, associated with EMT, are hypomethylated and overexpressed in lung adenocarcinoma and link to unfavorable prognosis
por: Wang, Wenlong, et al.
Publicado: (2020)

Krt14 and Krt15 differentially regulate regenerative properties and differentiation potential of airway basal cells
por: Ievlev, Vitaly, et al.
Publicado: (2023)

Prognostic significance of KRT19 in Lung Squamous Cancer
por: Yuan, Xun, et al.
Publicado: (2021)

The role of KRT17 in colorectal cancer
por: Ujiie, Daisuke, et al.
Publicado: (2021)

Combined drug therapeutic strategies for the effective treatment of Triple Negative Breast Cancer
por: Chalakur-Ramireddy, Naveen K.R., et al.
Publicado: (2018)

A KRT6A and a Novel KRT16 Gene Mutations in Chinese Patients with Pachyonychia Congenita
por: Gong, Li, et al.
Publicado: (2021)

A Comprehensive Analysis of KRT19 Combined with Immune Infiltration to Predict Breast Cancer Prognosis
por: Mi, Lusi, et al.
Publicado: (2022)

A Sporadic Neonatal Case of Epidermolysis Bullosa Simplex Generalized Intermediate with KRT5 and KRT14 Gene Mutations
por: Wakiguchi, Hiroyuki, et al.
Publicado: (2016)

Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation
por: Kuony, Alison, et al.
Publicado: (2017)

Enhanced Therapeutic Efficacy of Combining Losartan and Chemo-Immunotherapy for Triple Negative Breast Cancer
por: Zhao, Qing, et al.
Publicado: (2022)

Recurrent KRT10 Variant in Ichthyosis with Confetti
por: TAKEICHI, Takuya, et al.
Publicado: (2020)

Analysis of KRT5 and KRT14 gene mutations and mode of inheritance in Iranian patients with clinical suspicion of Epidermolysis bullosa simplex
por: Khani, Pouria, et al.
Publicado: (2020)

Whole-transcriptome bioinformatics revealed HTRA3, KRT8, KRT17, and RHEX as novel targets in acute myeloid leukaemia
por: El-Masry, Omar S., et al.
Publicado: (2022)

Triple-Negative Breast Cancer: Adjuvant Therapeutic Options
por: Gucalp, Ayca, et al.
Publicado: (2011)

Therapeutic landscape in mutational triple negative breast cancer
por: Shi, Yaqin, et al.
Publicado: (2018)

Targeted Therapeutic Strategies for Triple-Negative Breast Cancer
por: Li, Ying, et al.
Publicado: (2021)

Establishing the promising role of novel combination of triple therapeutics delivery using polymeric nanoparticles for Triple negative breast cancer therapy
por: Misra, Ranjita, et al.
Publicado: (2021)

Krt5(+)/Krt15(+) foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress
por: Moon, Hyeongsun, et al.
Publicado: (2019)

Severe Generalized Epidermolysis Bullosa Simplex in Two Hong Kong Children due to De Novo Variants in KRT14 and KRT5
por: Chong, Shuk Ching, et al.
Publicado: (2020)

Molecular Characteristics and Metastasis Predictor Genes of Triple-Negative Breast Cancer: A Clinical Study of Triple-Negative Breast Carcinomas
por: Kuo, Wen-Hung, et al.
Publicado: (2012)

Characters of KRT80 and its roles in neoplasms diseases
por: Wei, Xin‐Yuan, et al.
Publicado: (2023)

Long non-coding antisense RNA KRT7-AS is activated in gastric cancers and supports cancer cell progression by increasing KRT7 expression
por: Huang, Binbin, et al.
Publicado: (2016)

Stemness signature and targeted therapeutic drugs identification for Triple Negative Breast Cancer
por: Gul, Samina, et al.
Publicado: (2023)

Therapeutic Strategies for Metastatic Triple-Negative Breast Cancers: From Negative to Positive
por: Nandini, Dey, et al.
Publicado: (2021)

Combined Inhibition of ATR and WEE1 as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer
por: Jin, Juan, et al.
Publicado: (2018)

Novel therapeutic strategies for patients with triple-negative breast cancer
por: Zhang, Jun-Fei, et al.
Publicado: (2016)

CAPER as a therapeutic target for triple negative breast cancer
por: Campbell, Mallory C., et al.
Publicado: (2018)

Novel therapeutic strategies in the treatment of triple-negative breast cancer
por: Oualla, Karima, et al.
Publicado: (2017)

Emerging Therapeutic Drugs in Metastatic Triple-Negative Breast Cancer
por: Cipriano, Élia, et al.
Publicado: (2021)

Molecular Targets and Promising Therapeutics of Triple-Negative Breast Cancer
por: Ryu, Won-Ji, et al.
Publicado: (2021)

Pathogenesis and Potential Therapeutic Targets for Triple-Negative Breast Cancer
por: Li, Chia-Jung, et al.
Publicado: (2021)

Recent advances in therapeutic strategies for triple-negative breast cancer
por: Li, Yun, et al.
Publicado: (2022)

On the Therapeutic Potential of ERK4 in Triple-Negative Breast Cancer
por: Boudghene-Stambouli, Fadia, et al.
Publicado: (2022)

Ferroptosis and triple-negative breast cancer: Potential therapeutic targets
por: Xu, Na, et al.
Publicado: (2022)

mRNA-Expression of KRT5 and KRT20 Defines Distinct Prognostic Subgroups of Muscle-Invasive Urothelial Bladder Cancer Correlating with Histological Variants
por: Eckstein, Markus, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_p6cgrrmavf8n1uco2m4p1j3mde