Comparison of the inactivation capacity of various UV wavelengths on SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a worldwide pandemic. Ultraviolet (UV) is regarded as a very powerful tool against SARS-CoV-2. However, the inactivating effects of different UV wavelengths on SARS-CoV-2 under the same conditions have hardly been compared. Here, we...

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Detalles Bibliográficos
Autores principales: Matsuura, Ryosuke, Lo, Chieh-Wen, Ogawa, Takayo, Nakagawa, Masaru, Takei, Masami, Matsumoto, Yasunobu, Wada, Satoshi, Aida, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638801/
https://www.ncbi.nlm.nih.gov/pubmed/36373011
http://dx.doi.org/10.1016/j.bbrep.2022.101379
Descripción
Sumario:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a worldwide pandemic. Ultraviolet (UV) is regarded as a very powerful tool against SARS-CoV-2. However, the inactivating effects of different UV wavelengths on SARS-CoV-2 under the same conditions have hardly been compared. Here, we showed that SARS-CoV-2 cultured in Dulbecco's modified Eagle's medium and 2% fetal bovine serum was efficiently inactivated by irradiation with 222, 254, and 265 wavelengths UV, but not at 308 nm. In addition, it was revealed that UV absorption by DMEM-2% FBS is very efficient at 222 nm. Our results present potentially important information for selecting the optimum UV wavelength according to the application.

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