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Positively charged nanocomplex modulates dendritic cell differentiation to enhance Th1 immune response

Most existing vaccines use activators that polarize the immune response to T-helper (Th) 2 response for antibody production. Our positively charged chitosan (Cs)-based nanocomplex (CNC) drives the Th1 response through unknown mechanisms. As receptors for the positively charged CNC are not determined...

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Detalles Bibliográficos
Autores principales: Wu, Yan-Wei, Wang, Wan-Yu, Chen, Yu-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638821/
https://www.ncbi.nlm.nih.gov/pubmed/36353390
http://dx.doi.org/10.1016/j.mtbio.2022.100480