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E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2

Aberrant activation of inflammation signaling triggered by tumor necrosis factor α (TNF‐α), interleukin‐1 (IL‐1), and interleukin‐17 (IL‐17) is associated with immunopathology. Here, we identify neural precursor cells expressed developmentally down‐regulated gene 4‐like (NEDD4L), a HECT type E3 liga...

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Detalles Bibliográficos
Autores principales:	Li, Hui, Wang, Ning, Jiang, Yu, Wang, Haofei, Xin, Zengfeng, An, Huazhang, Pan, Hao, Ma, Wangqian, Zhang, Ting, Wang, Xiaojian, Lin, Wenlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638856/ https://www.ncbi.nlm.nih.gov/pubmed/36161689 http://dx.doi.org/10.15252/embr.202254603

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