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Molecular basis of cyclic tetra-oligoadenylate processing by small standalone CRISPR-Cas ring nucleases
Standalone ring nucleases are CRISPR ancillary proteins, which downregulate the immune response of Type III CRISPR-Cas systems by cleaving cyclic oligoadenylates (cA) second messengers. Two genes with this function have been found within the Sulfolobus islandicus (Sis) genome. They code for a long p...
Autores principales: | Molina, Rafael, Garcia-Martin, Ricardo, López-Méndez, Blanca, Jensen, Anne Louise Grøn, Ciges-Tomas, J Rafael, Marchena-Hurtado, Javier, Stella, Stefano, Montoya, Guillermo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638899/ https://www.ncbi.nlm.nih.gov/pubmed/36271789 http://dx.doi.org/10.1093/nar/gkac923 |
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