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Structure and mechanism of the type I-G CRISPR effector

Type I CRISPR systems are the most common CRISPR type found in bacteria. They use a multisubunit effector, guided by crRNA, to detect and bind dsDNA targets, forming an R-loop and recruiting the Cas3 enzyme to facilitate target DNA destruction, thus providing immunity against mobile genetic elements...

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Detalles Bibliográficos
Autores principales:	Shangguan, Qilin, Graham, Shirley, Sundaramoorthy, Ramasubramanian, White, Malcolm F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638904/ https://www.ncbi.nlm.nih.gov/pubmed/36305833 http://dx.doi.org/10.1093/nar/gkac925

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