Transcription-coupled donor DNA expression increases homologous recombination for efficient genome editing

Genomes can be edited by homologous recombination stimulated by CRISPR/Cas9 [clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated peptide 9]-induced DNA double-strand breaks. However, this approach is inefficient for inserting or deleting long fragments in mammalian c...

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Detalles Bibliográficos
Autores principales: Gao, Kaixuan, Zhang, Xuedi, Zhang, Zhenwu, Wu, Xiangyu, Guo, Yan, Fu, Pengchong, Sun, Angyang, Peng, Ju, Zheng, Jie, Yu, Pengfei, Wang, Tengfei, Ye, Qinying, Jiang, Jingwei, Wang, Haopeng, Lin, Chao-Po, Gao, Guanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638910/
https://www.ncbi.nlm.nih.gov/pubmed/35929067
http://dx.doi.org/10.1093/nar/gkac676

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