ATM-mediated ELL phosphorylation enhances its self-association through increased EAF1 interaction and inhibits global transcription during genotoxic stress

Mammalian cells immediately inhibit transcription upon exposure to genotoxic stress to avoid fatal collision between ongoing transcription and newly recruited DNA repair machineries to protect genomic integrity. However, mechanisms of this early transcriptional inhibition are poorly understood. In t...

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Detalles Bibliográficos
Autores principales: Pal, Sujay, Yadav, Dipika, Biswas, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638944/
https://www.ncbi.nlm.nih.gov/pubmed/36305813
http://dx.doi.org/10.1093/nar/gkac943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638944/
https://www.ncbi.nlm.nih.gov/pubmed/36305813
http://dx.doi.org/10.1093/nar/gkac943

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