Cargando…

Organocatalytic Asymmetric Synthesis of SynVesT-1, a Synaptic Density Positron Emission Tomography Imaging Agent

[Image: see text] Heterocyclic nonacetamide ligands are used as positron emission tomography (PET) imaging agents of the synaptic vesicle glycoprotein 2A (SV2A), with potential applications in the diagnosis of various neuropsychiatric diseases. To date, the main synthetic strategy to access these op...

Descripción completa

Detalles Bibliográficos
Autores principales:	McErlain, Holly, McLean, Euan B., Morgan, Timaeus E. F., Burianova, Valeria K., Tavares, Adriana A. S., Sutherland, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639009/ https://www.ncbi.nlm.nih.gov/pubmed/36222243 http://dx.doi.org/10.1021/acs.joc.2c01895

Ejemplares similares

Lower synaptic density associated with gaming disorder: an (18)F-SynVesT-1 PET imaging study
por: Hou, Jiale, et al.
Publicado: (2023)

(18)F-SynVesT-1 PET/MR Imaging of the Effect of Gut Microbiota on Synaptic Density and Neurite Microstructure: A Preclinical Pilot Study
por: Yi, Sue Y., et al.
Publicado: (2022)

Cortical abnormalities of synaptic vesicle protein 2A in focal cortical dysplasia type II identified in vivo with (18)F-SynVesT-1 positron emission tomography imaging
por: Tang, Yongxiang, et al.
Publicado: (2022)

Validation, kinetic modeling, and test-retest reproducibility of [(18)F]SynVesT-1 for PET imaging of synaptic vesicle glycoprotein 2A in mice
por: Bertoglio, Daniele, et al.
Publicado: (2022)

Preliminary Assessment of Reference Region Quantification and Reduced Scanning Times for [(18)F]SynVesT-1 PET in Parkinson's Disease
por: Smart, Kelly, et al.
Publicado: (2023)

Palladium-Catalyzed C–P Bond-Forming Reactions of Aryl Nonaflates Accelerated by Iodide
por: McErlain, Holly, et al.
Publicado: (2021)

Post Flywheel Squat Potentiation of Vertical and Horizontal Ground Reaction Force Parameters during Jumps and Changes of Direction
por: McErlain-Naylor, Stuart A., et al.
Publicado: (2021)

Organocatalytic asymmetric chlorinative dearomatization of naphthols
por: Yin, Qin, et al.
Publicado: (2015)

¿Loque veo ves? ó ¿Lo que ves veo?.
por: Barradas Mendoza, Elba Estela
Publicado: (1999)

Organocatalytic asymmetric synthesis of P-stereogenic molecules
por: Liu, Junyang, et al.
Publicado: (2023)

Éste que ves /
por: Velasco, Xavier
Publicado: (2009)

Éste que ves /
por: Velasco, Xavier
Publicado: (2007)

Towards an asymmetric organocatalytic α-cyanation of β-ketoesters
por: Chowdhury, Raghunath, et al.
Publicado: (2015)

Towards an Asymmetric Organocatalytic α-Azidation of β-Ketoesters
por: Tiffner, Maximilian, et al.
Publicado: (2018)

Organocatalytic Asymmetric Synthesis of Si-Stereogenic Silyl Ethers
por: Zhou, Hui, et al.
Publicado: (2022)

Organocatalytic chiral polymeric nanoparticles for asymmetric aldol reaction
por: Abuaf, Meir, et al.
Publicado: (2023)

The Effect of Flywheel Inertia on Peak Power and Its Inter-session Reliability During Two Unilateral Hamstring Exercises: Leg Curl and Hip Extension
por: de Keijzer, Kevin L., et al.
Publicado: (2022)

Organocatalytic asymmetric addition of malonates to unsaturated 1,4-diketones
por: Žari, Sergei, et al.
Publicado: (2012)

Organocatalytic asymmetric fluorination of α-chloroaldehydes involving kinetic resolution
por: Shibatomi, Kazutaka, et al.
Publicado: (2014)

Absolute and relative facial selectivities in organocatalytic asymmetric chlorocyclization reactions
por: Salehi Marzijarani, Nastaran, et al.
Publicado: (2018)

Organocatalytic asymmetric nitroso aldol reaction of α-substituted malonamates
por: Gupta, Ekta, et al.
Publicado: (2022)

Estas ruinas que ves /
por: Ibargüengoitia, Jorge, 1928-1983
Publicado: (1991)

Estas ruinas que ves
por: Ibargüengoitia, Jorge, 1928-1983
Publicado: (1975)

Meson spectroscopy at VES and COMPASS
por: Ryabchikov, Dmitry
Publicado: (2019)

On-field rehabilitation in football: Current knowledge, applications and future directions
por: Armitage, Mark, et al.
Publicado: (2022)

Asymmetric total synthesis of smyrindiol employing an organocatalytic aldol key step
por: Enders, Dieter, et al.
Publicado: (2012)

Organocatalytic asymmetric allylic amination of Morita–Baylis–Hillman carbonates of isatins
por: Zhang, Hang, et al.
Publicado: (2012)

Recent advances in organocatalytic asymmetric aza-Michael reactions of amines and amides
por: Sharma, Pratibha, et al.
Publicado: (2021)

Organocatalytic asymmetric synthesis of α-amino esters from sulfoxonium ylides
por: Guo, Wengang, et al.
Publicado: (2021)

Chiral Phosphoric Acids as Versatile Tools for Organocatalytic Asymmetric Transfer Hydrogenations
por: Pálvölgyi, Ádám Márk, et al.
Publicado: (2021)

Design of an Organocatalytic Asymmetric (4 + 3) Cycloaddition of 2-Indolylalcohols with Dienolsilanes
por: Ouyang, Jie, et al.
Publicado: (2022)

Asymmetric Organocatalytic Homologation: Access to Diverse Chiral Trifluoromethyl Organoboron Species
por: Jayarajan, Ramasamy, et al.
Publicado: (2022)

¿Qué ves? / ¿Qué es? / Mardonio Carballo Manuel ; edición de Marta Acevedo.
por: Méndez, Royer Omar
Publicado: (2003)

SynGAP isoforms exert opposing effects on synaptic strength
por: McMahon, A.C., et al.
Publicado: (2012)

Cómo la ves? : la televisión mexicana y su público /
por: Jara Elías, Rubén
Publicado: (2007)

Estas ruinas que ves = These ruins you see /
por: Castillo Deball, Mariana
Publicado: (2008)

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives
por: Auria-Luna, Fernando, et al.
Publicado: (2018)

Organocatalytic Asymmetric Conjugate Addition of Aldehydes to Maleimides and Nitroalkenes in Deep Eutectic Solvents
por: Torregrosa-Chinillach, Alejandro, et al.
Publicado: (2019)

Organocatalytic asymmetric formal oxidative coupling for the construction of all-aryl quaternary stereocenters
por: Li, Zhiyang, et al.
Publicado: (2021)

Organocatalytic Asymmetric [2 + 4] Cycloadditions of 3-Vinylindoles with ortho-Quinone Methides
por: Liu, Si-Jia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cfdsf0asavbohksv1b8nbcnoq6