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Echinacoside inhibited cardiomyocyte pyroptosis and improved heart function of HF rats induced by isoproterenol via suppressing NADPH/ROS/ER stress

Prevalence of heart failure (HF) continues to rise over time and is a global difficult problem; new drug targets are urgently needed. In recent years, pyroptosis is confirmed to promote cardiac remodelling and HF. Echinacoside (ECH) is a natural phenylethanoid glycoside and is the major active compo...

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Detalles Bibliográficos
Autores principales: Ni, YaJuan, Zhang, Jing, Zhu, Wenjing, Duan, Yixuan, Bai, HongYuan, Luan, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639035/
https://www.ncbi.nlm.nih.gov/pubmed/36201630
http://dx.doi.org/10.1111/jcmm.17564

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